Bezt Frends is the 28th episode of Uncle Grandpa season 1, and the 28th overall episode of the series.
Uncle Grandpa makes best friend necklaces for everyone in the RV. Unfortunately for him, Pizza Steve did not accept the necklace, claiming that he is his own best friend. Uncle Grandpa believed there was another Pizza Steve present that was Pizza Steve's best friend, so he went through extreme measures to get rid of Pizza Steve so he could become Pizza Steve's friend. After every single one of those backfired, he ended up sending Pizza Steve to the moon.
He tells the others his plan to become Pizza Steve's best friend. The others explain to him that Pizza Steve actually meant that he was actually his own best friend and that Uncle Grandpa accidentally sent actual Pizza Steve to the moon and not a duplicate. So Uncle Grandpa has the RV drive up to the moon so he can go save Pizza Steve. They find Pizza Steve who informs them that his new best friend is Mooon Man. Uncle Grandpa challenges Mooon Man to a Pizza Steve trivia game where the winner is Pizza Steve's best friend.
Pizza Steve makes himself the host and begins to ask loaded questions that Uncle Grandpa can't answer. After Mooon Man gets all the questions correct, Pizza Steve asks one more question that he says renders all the other questions useless. Uncle Grandpa was able to answer this one correctly, so Pizza Steve takes Uncle Grandpa back as his best friend and goes home with him to the RV and accepts his friendship necklace.
- This episode and "1992 Called" aired back-to-back as a half-hour episode.
- The clown that was in the cabinet that Uncle Grandpa opened is a possible parody of Pennywise the Clown from the Stephen King movie It.
- The duck gun that Uncle Grandpa was using in the short was possibly a parody of the game Duck Hunt.
- The wolf that returned Pizza Steve to the RV after Uncle Grandpa left him in the forest is not only identical in appearace to the night wolves in Belly Bros, but the wolf also has the same voice as Festro from Secret Mountain Fort Awesome.
- Mooon Man parodies a character named "Mac Tonight", a mascot that was for McDonalds. Some people refer Mac Tonight as "Moon Man".